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3NPD

Crystal structure of a putative secreted protein (PA3611) from PSEUDOMONAS AERUGINOSA at 1.60 A resolution

Summary for 3NPD
Entry DOI10.2210/pdb3npd/pdb
Descriptorputative secreted protein, SULFATE ION, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... (5 entities in total)
Functional Keywordsstructural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, unknown function
Biological sourcePseudomonas aeruginosa
Total number of polymer chains1
Total formula weight14323.88
Authors
Joint Center for Structural Genomics (JCSG) (deposition date: 2010-06-28, release date: 2010-07-28, Last modification date: 2024-11-06)
Primary citationDas, D.,Chiu, H.J.,Farr, C.L.,Grant, J.C.,Jaroszewski, L.,Knuth, M.W.,Miller, M.D.,Tien, H.J.,Elsliger, M.A.,Deacon, A.M.,Godzik, A.,Lesley, S.A.,Wilson, I.A.
Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.
Proteins, 82:1086-1092, 2014
Cited by
PubMed Abstract: Pseudomonas aeruginosa is an opportunistic pathogen commonly found in humans and other organisms and is an important cause of infection especially in patients with compromised immune defense mechanisms. The PA3611 gene of P. aeruginosa PAO1 encodes a secreted protein of unknown function, which has been recently classified into a small Pseudomonas-specific protein family called DUF4146. As part of our effort to extend structural coverage of novel protein space and provide a structure-based functional insight into new protein families, we report the crystal structure of PA3611, the first structural representative of the DUF4146 protein family.
PubMed: 24174223
DOI: 10.1002/prot.24455
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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数据于2025-06-18公开中

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