3NPD
Crystal structure of a putative secreted protein (PA3611) from PSEUDOMONAS AERUGINOSA at 1.60 A resolution
Summary for 3NPD
Entry DOI | 10.2210/pdb3npd/pdb |
Descriptor | putative secreted protein, SULFATE ION, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... (5 entities in total) |
Functional Keywords | structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, unknown function |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 14323.88 |
Authors | Joint Center for Structural Genomics (JCSG) (deposition date: 2010-06-28, release date: 2010-07-28, Last modification date: 2024-11-06) |
Primary citation | Das, D.,Chiu, H.J.,Farr, C.L.,Grant, J.C.,Jaroszewski, L.,Knuth, M.W.,Miller, M.D.,Tien, H.J.,Elsliger, M.A.,Deacon, A.M.,Godzik, A.,Lesley, S.A.,Wilson, I.A. Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family. Proteins, 82:1086-1092, 2014 Cited by PubMed Abstract: Pseudomonas aeruginosa is an opportunistic pathogen commonly found in humans and other organisms and is an important cause of infection especially in patients with compromised immune defense mechanisms. The PA3611 gene of P. aeruginosa PAO1 encodes a secreted protein of unknown function, which has been recently classified into a small Pseudomonas-specific protein family called DUF4146. As part of our effort to extend structural coverage of novel protein space and provide a structure-based functional insight into new protein families, we report the crystal structure of PA3611, the first structural representative of the DUF4146 protein family. PubMed: 24174223DOI: 10.1002/prot.24455 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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