3NPD

Crystal structure of a putative secreted protein (PA3611) from PSEUDOMONAS AERUGINOSA at 1.60 A resolution

3NPD の概要

• エントリーDOI: 10.2210/pdb3npd/pdb
• 分子名称: putative secreted protein, SULFATE ION, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... (5 entities in total)
• 機能のキーワード: structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, unknown function
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14323.88

構造登録者

Joint Center for Structural Genomics (JCSG) (登録日: 2010-06-28, 公開日: 2010-07-28, 最終更新日: 2024-11-06)

主引用文献

Das, D.,Chiu, H.J.,Farr, C.L.,Grant, J.C.,Jaroszewski, L.,Knuth, M.W.,Miller, M.D.,Tien, H.J.,Elsliger, M.A.,Deacon, A.M.,Godzik, A.,Lesley, S.A.,Wilson, I.A.
Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.
Proteins, 82:1086-1092, 2014

PubMed Abstract: Pseudomonas aeruginosa is an opportunistic pathogen commonly found in humans and other organisms and is an important cause of infection especially in patients with compromised immune defense mechanisms. The PA3611 gene of P. aeruginosa PAO1 encodes a secreted protein of unknown function, which has been recently classified into a small Pseudomonas-specific protein family called DUF4146. As part of our effort to extend structural coverage of novel protein space and provide a structure-based functional insight into new protein families, we report the crystal structure of PA3611, the first structural representative of the DUF4146 protein family.

PubMed: 24174223
DOI: 10.1002/prot.24455

実験手法

X-RAY DIFFRACTION (1.6 Å)