3NF3
Crystal structure of BoNT/A LC with JTH-NB-7239 peptide
Summary for 3NF3
Entry DOI | 10.2210/pdb3nf3/pdb |
Related PRD ID | PRD_000997 |
Descriptor | BoNT/A, JTH-NB72-39 inhibitor, ZINC ION, ... (5 entities in total) |
Functional Keywords | botulinum neurotoxin, snare, botulism, inhibition, metalloprotease, neurotransmission, neuromuscular junction, hydrolase, membrane, metal-binding, protease, secreted, toxin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Clostridium botulinum |
Total number of polymer chains | 2 |
Total formula weight | 49779.36 |
Authors | Zuniga, J.E. (deposition date: 2010-06-09, release date: 2010-07-21, Last modification date: 2023-11-22) |
Primary citation | Zuniga, J.E.,Hammill, J.T.,Drory, O.,Nuss, J.E.,Burnett, J.C.,Gussio, R.,Wipf, P.,Bavari, S.,Brunger, A.T. Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A. Plos One, 5:e11378-e11378, 2010 Cited by PubMed: 20614028DOI: 10.1371/journal.pone.0011378 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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