3NF3

Crystal structure of BoNT/A LC with JTH-NB-7239 peptide

Summary for 3NF3

Entry DOI	10.2210/pdb3nf3/pdb
Related PRD ID	PRD_000997
Descriptor	BoNT/A, JTH-NB72-39 inhibitor, ZINC ION, ... (5 entities in total)
Functional Keywords	botulinum neurotoxin, snare, botulism, inhibition, metalloprotease, neurotransmission, neuromuscular junction, hydrolase, membrane, metal-binding, protease, secreted, toxin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Clostridium botulinum
Total number of polymer chains	2
Total formula weight	49779.36
Authors	Zuniga, J.E. (deposition date: 2010-06-09, release date: 2010-07-21, Last modification date: 2023-11-22)
Primary citation	Zuniga, J.E.,Hammill, J.T.,Drory, O.,Nuss, J.E.,Burnett, J.C.,Gussio, R.,Wipf, P.,Bavari, S.,Brunger, A.T. Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A. Plos One, 5:e11378-e11378, 2010 Cited by PubMed: 20614028 DOI: 10.1371/journal.pone.0011378 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation