3NC9

X-ray structure of ketohexokinase complexed with an indazole compound

Summary for 3NC9

Entry DOI	10.2210/pdb3nc9/pdb
Related	3NBV 3NBW 3NC2 3NCA
Descriptor	Ketohexokinase, N-[3-(methylsulfanyl)-1-phenyl-1H-indazol-6-yl]piperidine-4-carboxamide, SULFATE ION, ... (4 entities in total)
Functional Keywords	ketohexokinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	69078.26
Authors	Abad, M.C.,Gibbs, A.C.,Spurlino, J.C. (deposition date: 2010-06-04, release date: 2010-12-22, Last modification date: 2023-09-06)
Primary citation	Gibbs, A.C.,Abad, M.C.,Zhang, X.,Tounge, B.A.,Lewandowski, F.A.,Struble, G.T.,Sun, W.,Sui, Z.,Kuo, L.C. Electron density guided fragment-based lead discovery of ketohexokinase inhibitors. J.Med.Chem., 53:7979-7991, 2010 Cited by PubMed: 21033679 DOI: 10.1021/jm100677s PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation