3NC9
X-ray structure of ketohexokinase complexed with an indazole compound
Summary for 3NC9
Entry DOI | 10.2210/pdb3nc9/pdb |
Related | 3NBV 3NBW 3NC2 3NCA |
Descriptor | Ketohexokinase, N-[3-(methylsulfanyl)-1-phenyl-1H-indazol-6-yl]piperidine-4-carboxamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ketohexokinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 69078.26 |
Authors | Abad, M.C.,Gibbs, A.C.,Spurlino, J.C. (deposition date: 2010-06-04, release date: 2010-12-22, Last modification date: 2023-09-06) |
Primary citation | Gibbs, A.C.,Abad, M.C.,Zhang, X.,Tounge, B.A.,Lewandowski, F.A.,Struble, G.T.,Sun, W.,Sui, Z.,Kuo, L.C. Electron density guided fragment-based lead discovery of ketohexokinase inhibitors. J.Med.Chem., 53:7979-7991, 2010 Cited by PubMed: 21033679DOI: 10.1021/jm100677s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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