3NC8

Crystal Structure of BlaC-E166A covalently bound with Mecillinam

Summary for 3NC8

• Entry DOI: 10.2210/pdb3nc8/pdb
• Descriptor: Beta-lactamase, PHOSPHATE ION, 2-[(1R)-1-{[(E)-azepan-1-ylmethylidene]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ... (4 entities in total)
• Functional Keywords: penicillin binding protein, beta-lactam covalent adduct, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 28827.04

Authors

Tremblay, L.W.,Blanchard, J.S. (deposition date: 2010-06-04, release date: 2011-12-14, Last modification date: 2023-09-06)

• Primary citation: Tremblay, L.W.,Blanchard, J.S.; BlaC-E166A covalently bound with cephalosporins and penicillins; To be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)