3NBF

Q28E mutant of hera helicase N-terminal domain bound to 8-oxo-ADP

Summary for 3NBF

Entry DOI	10.2210/pdb3nbf/pdb
Related	3MWJ 3MWK 3MWL
Descriptor	Heat resistant RNA dependent ATPase, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphono hydrogen phosphate, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate, ... (4 entities in total)
Functional Keywords	rna helicase, ribosome biogenesis, atp hydrolysis, base specificity, thermostability, hydrolase
Biological source	Thermus thermophilus
Total number of polymer chains	4
Total formula weight	93124.62
Authors	Rudolph, M.G.,Klostermeier, D. (deposition date: 2010-06-03, release date: 2011-03-23, Last modification date: 2023-11-01)
Primary citation	Strohmeier, J.,Hertel, I.,Diederichsen, U.,Rudolph, M.G.,Klostermeier, D. Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop. Biol.Chem., 392:357-369, 2011 Cited by PubMed: 21391900 DOI: 10.1515/BC.2011.034 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation