3NBF

Q28E mutant of hera helicase N-terminal domain bound to 8-oxo-ADP

3NBF の概要

• エントリーDOI: 10.2210/pdb3nbf/pdb
• 関連するPDBエントリー: 3MWJ 3MWK 3MWL
• 分子名称: Heat resistant RNA dependent ATPase, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphono hydrogen phosphate, [(2R,3S,4R,5R)-5-(6-azanyl-8-oxo-7H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate, ... (4 entities in total)
• 機能のキーワード: rna helicase, ribosome biogenesis, atp hydrolysis, base specificity, thermostability, hydrolase
• 由来する生物種: Thermus thermophilus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 93124.62

構造登録者

Rudolph, M.G.,Klostermeier, D. (登録日: 2010-06-03, 公開日: 2011-03-23, 最終更新日: 2023-11-01)

• 主引用文献: Strohmeier, J.,Hertel, I.,Diederichsen, U.,Rudolph, M.G.,Klostermeier, D.; Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.; Biol.Chem., 392:357-369, 2011; PubMed: 21391900; DOI: 10.1515/BC.2011.034

実験手法

X-RAY DIFFRACTION (1.9 Å)