Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin

Summary for 3NB7

Related2OQO 3D3H 3NB6
DescriptorPenicillin-binding protein 1A (1 entity in total)
Functional Keywordsglycosyltransferases, peptidoglycan glycosyltransferase, polysaccharides, cell wall, antibiotics, moenomycin, transferase
Biological sourceAquifex aeolicus
Cellular locationCell inner membrane; Single-pass type II membrane protein (By similarity) O66874
Total number of polymer chains1
Total molecular weight22912.43
Sliz, P.,Yuan, Y.,Walker, S. (deposition date: 2010-06-02, release date: 2011-05-18, Last modification date: 2011-07-13)
Primary citation
Fuse, S.,Tsukamoto, H.,Yuan, Y.,Wang, T.S.,Zhang, Y.,Bolla, M.,Walker, S.,Sliz, P.,Kahne, D.
Functional and structural analysis of a key region of the cell wall inhibitor moenomycin.
Acs Chem.Biol., 5:701-711, 2010
PubMed: 20496948 (PDB entries with the same primary citation)
DOI: 10.1021/cb100048q
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers182.3%6.1%5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report