3N9V
Crystal Structure of INPP5B
Summary for 3N9V
Entry DOI | 10.2210/pdb3n9v/pdb |
Related | 3MTC 3NR8 |
Descriptor | Type II inositol-1,4,5-trisphosphate 5-phosphatase, MAGNESIUM ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | inpp5b, phosphoinositide 5-phosphatase, inositol signalling, phosphatase, magnesium, structural genomics, sgc, sgc stockholm, structural genomics consortium, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol: P32019 |
Total number of polymer chains | 2 |
Total formula weight | 72484.75 |
Authors | Tresaugues, L.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kol, S.,Kotenyova, T.,Moche, M.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,van der Berg, S.,Wahlberg, E.,Weigelt, J.,Wisniewska, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2010-05-31, release date: 2010-07-28, Last modification date: 2023-09-06) |
Primary citation | Tresaugues, L.,Silvander, C.,Flodin, S.,Welin, M.,Nyman, T.,Graslund, S.,Hammarstrom, M.,Berglund, H.,Nordlund, P. Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases Structure, 22:744-755, 2014 Cited by PubMed: 24704254DOI: 10.1016/j.str.2014.01.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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