3N9V

Crystal Structure of INPP5B

Summary for 3N9V

• Entry DOI: 10.2210/pdb3n9v/pdb
• Related: 3MTC 3NR8
• Descriptor: Type II inositol-1,4,5-trisphosphate 5-phosphatase, MAGNESIUM ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: inpp5b, phosphoinositide 5-phosphatase, inositol signalling, phosphatase, magnesium, structural genomics, sgc, sgc stockholm, structural genomics consortium, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytosol: P32019
• Total number of polymer chains: 2
• Total formula weight: 72484.75

Authors

Tresaugues, L.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kol, S.,Kotenyova, T.,Moche, M.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,van der Berg, S.,Wahlberg, E.,Weigelt, J.,Wisniewska, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2010-05-31, release date: 2010-07-28, Last modification date: 2023-09-06)

• Primary citation: Tresaugues, L.,Silvander, C.,Flodin, S.,Welin, M.,Nyman, T.,Graslund, S.,Hammarstrom, M.,Berglund, H.,Nordlund, P.; Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases; Structure, 22:744-755, 2014; PubMed: 24704254; DOI: 10.1016/j.str.2014.01.013

Experimental method

X-RAY DIFFRACTION (2.65 Å)