3N7W

Crystal Structure of BlaC-E166A covalently bound with Amoxicillin

Summary for 3N7W

• Entry DOI: 10.2210/pdb3n7w/pdb
• Descriptor: Beta-lactamase, 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: penicillin binding protein, beta-lactam covalent adduct, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 28772.05

Authors

Tremblay, L.W.,Blanchard, J.S. (deposition date: 2010-05-27, release date: 2011-12-14, Last modification date: 2023-09-06)

• Primary citation: Tremblay, L.W.,Blanchard, J.S.; BlaC-E166A Bound with btea-lactams of all classes; To be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)