3N1F

Crystal Structure of IhhN bound to CDOFn3

Summary for 3N1F

Entry DOI	10.2210/pdb3n1f/pdb
Related	3N1G 3N1M 3N1O 3N1P 3N1Q 3N1R
Descriptor	Indian hedgehog protein, Cell adhesion molecule-related/down-regulated by oncogenes, ZINC ION, ... (5 entities in total)
Functional Keywords	binding sites, cell adhesion molecules, cell cycle proteins, cell line, conserved sequence, fibronectins, hedgehog proteins, immunoglobulin g, membrane glycoproteins, membrane proteins, protein binding, tertiary, receptors, cell surface, sequence homology, signal transduction, tumor suppressor proteins
Biological source	Homo sapiens (human) More
Cellular location	Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side (By similarity). Indian hedgehog protein C-product: Secreted, extracellular space (By similarity): Q14623 Membrane; Single-pass membrane protein (Potential): Q4KMG0
Total number of polymer chains	4
Total formula weight	61937.74
Authors	Kavran, J.M.,Leahy, D.J. (deposition date: 2010-05-15, release date: 2010-06-02, Last modification date: 2023-09-06)
Primary citation	Kavran, J.M.,Ward, M.D.,Oladosu, O.O.,Mulepati, S.,Leahy, D.J. All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285:24584-24590, 2010 Cited by PubMed: 20519495 DOI: 10.1074/jbc.M110.131680 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation