3N1F

Crystal Structure of IhhN bound to CDOFn3

3N1F の概要

• エントリーDOI: 10.2210/pdb3n1f/pdb
• 関連するPDBエントリー: 3N1G 3N1M 3N1O 3N1P 3N1Q 3N1R
• 分子名称: Indian hedgehog protein, Cell adhesion molecule-related/down-regulated by oncogenes, ZINC ION, ... (5 entities in total)
• 機能のキーワード: binding sites, cell adhesion molecules, cell cycle proteins, cell line, conserved sequence, fibronectins, hedgehog proteins, immunoglobulin g, membrane glycoproteins, membrane proteins, protein binding, tertiary, receptors, cell surface, sequence homology, signal transduction, tumor suppressor proteins
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side (By similarity). Indian hedgehog protein C-product: Secreted, extracellular space (By similarity): Q14623; Membrane; Single-pass membrane protein (Potential): Q4KMG0
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 61937.74

構造登録者

Kavran, J.M.,Leahy, D.J. (登録日: 2010-05-15, 公開日: 2010-06-02, 最終更新日: 2023-09-06)

• 主引用文献: Kavran, J.M.,Ward, M.D.,Oladosu, O.O.,Mulepati, S.,Leahy, D.J.; All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.; J.Biol.Chem., 285:24584-24590, 2010; PubMed: 20519495; DOI: 10.1074/jbc.M110.131680

実験手法

X-RAY DIFFRACTION (1.6 Å)