3MXO

Crystal structure oh human phosphoglycerate mutase family member 5 (PGAM5)

3MXO の概要

• エントリーDOI: 10.2210/pdb3mxo/pdb
• 分子名称: Serine/threonine-protein phosphatase PGAM5, mitochondrial, 1,2-ETHANEDIOL, TETRAETHYLENE GLYCOL, ... (7 entities in total)
• 機能のキーワード: pgam5, phosphoglycerate mutase family member 5, bxlbv68, mgc5352 protein, structural genomics consortium, sgc, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion outer membrane ; Single-pass membrane protein : Q96HS1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47459.01

構造登録者

Chaikuad, A.,Alfano, I.,Picaud, S.,Filippakopoulos, P.,Barr, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Takeda, K.,Ichijo, H.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2010-05-07, 公開日: 2010-09-15, 最終更新日: 2023-07-26)

• 主引用文献: Chaikuad, A.,Filippakopoulos, P.,Marcsisin, S.R.,Picaud, S.,Schroder, M.,Sekine, S.,Ichijo, H.,Engen, J.R.,Takeda, K.,Knapp, S.; Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly.; Structure, 25:1089-1099.e3, 2017; PubMed: 28648608; DOI: 10.1016/j.str.2017.05.020

実験手法

X-RAY DIFFRACTION (1.7 Å)