3MWO

Human carbonic anhydrase II in a doubled monoclinic cell: a re-determination

「3KS1」から置き換えられました

3MWO の概要

• エントリーDOI: 10.2210/pdb3mwo/pdb
• 分子名称: Carbonic anhydrase 2, ZINC ION (3 entities in total)
• 機能のキーワード: doubled unit cell, lyase, pseudosymmetry, translational ncs
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm : P00918
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58708.94

構造登録者

Robbins, A.H.,McKenna, R. (登録日: 2010-05-06, 公開日: 2010-06-09, 最終更新日: 2023-09-06)

主引用文献

Robbins, A.H.,Domsic, J.F.,Agbandje-McKenna, M.,McKenna, R.
Emerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinic P2(1) with a doubled a axis.
Acta Crystallogr.,Sect.D, 66:950-952, 2010

PubMed Abstract: The crystal structure of human carbonic anhydrase II in the monoclinic P2(1) space group with a doubled a axis from that of the usually observed unit cell has recently been reported, with one of the two molecules in the asymmetric unit demonstrating rotational disorder [Robbins et al. (2010), Acta Cryst. D66, 628-634]. The structure has been redetermined, with the coordinates of both pseudo-symmetrically related molecules in the crystallographic asymmetric unit translated by x' = x +/- 1/4, and no rotational disorder is observed. This corresponds to a different choice of how the four molecules in the unit cell should be grouped into pairs that represent a single asymmetric unit.

PubMed: 20693695
DOI: 10.1107/S0907444910023723

実験手法

X-RAY DIFFRACTION (1.4 Å)