3MPC

The crystal structure of a Fn3-like protein from Clostridium thermocellum

Summary for 3MPC

• Entry DOI: 10.2210/pdb3mpc/pdb
• Descriptor: Fn3-like protein, SULFATE ION (3 entities in total)
• Functional Keywords: fibronectin, fn(iii), fn3, unknown function
• Biological source: Clostridium thermocellum
• Total number of polymer chains: 2
• Total formula weight: 21855.81

Authors

Alahuhta, M.P.,Xu, Q.,Brunecky, R.,Lunin, V.V. (deposition date: 2010-04-26, release date: 2010-08-11, Last modification date: 2024-02-21)

Primary citation

Alahuhta, M.,Xu, Q.,Brunecky, R.,Adney, W.S.,Ding, S.Y.,Himmel, M.E.,Lunin, V.V.
Structure of a fibronectin type III-like module from Clostridium thermocellum.
Acta Crystallogr.,Sect.F, 66:878-880, 2010

PubMed Abstract: The 1.6 A resolution structure of a fibronectin type III-like module from Clostridium thermocellum (PDB code 3mpc) with two molecules in the asymmetric unit is reported. The crystals used for data collection belonged to space group P2(1)2(1)2(1), with unit-cell parameters a=35.43, b=45.73, c=107.72 A, and the structure was refined to an R factor of 0.166. Structural comparisons found over 800 similar structures in the Protein Data Bank. The broad range of different proteins or protein domains with high structural similarity makes it especially demanding to classify these proteins. Previous studies of fibronectin type III-like modules have indicated that they might function as ligand-binding modules, as a compact form of peptide linkers or spacers between other domains, as cellulose-disrupting modules or as proteins that help large enzyme complexes remain soluble.

PubMed: 20693658
DOI: 10.1107/S1744309110022529

Experimental method

X-RAY DIFFRACTION (1.6 Å)