3MPC

The crystal structure of a Fn3-like protein from Clostridium thermocellum

3MPC の概要

• エントリーDOI: 10.2210/pdb3mpc/pdb
• 分子名称: Fn3-like protein, SULFATE ION (3 entities in total)
• 機能のキーワード: fibronectin, fn(iii), fn3, unknown function
• 由来する生物種: Clostridium thermocellum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 21855.81

構造登録者

Alahuhta, M.P.,Xu, Q.,Brunecky, R.,Lunin, V.V. (登録日: 2010-04-26, 公開日: 2010-08-11, 最終更新日: 2024-02-21)

主引用文献

Alahuhta, M.,Xu, Q.,Brunecky, R.,Adney, W.S.,Ding, S.Y.,Himmel, M.E.,Lunin, V.V.
Structure of a fibronectin type III-like module from Clostridium thermocellum.
Acta Crystallogr.,Sect.F, 66:878-880, 2010

PubMed Abstract: The 1.6 A resolution structure of a fibronectin type III-like module from Clostridium thermocellum (PDB code 3mpc) with two molecules in the asymmetric unit is reported. The crystals used for data collection belonged to space group P2(1)2(1)2(1), with unit-cell parameters a=35.43, b=45.73, c=107.72 A, and the structure was refined to an R factor of 0.166. Structural comparisons found over 800 similar structures in the Protein Data Bank. The broad range of different proteins or protein domains with high structural similarity makes it especially demanding to classify these proteins. Previous studies of fibronectin type III-like modules have indicated that they might function as ligand-binding modules, as a compact form of peptide linkers or spacers between other domains, as cellulose-disrupting modules or as proteins that help large enzyme complexes remain soluble.

PubMed: 20693658
DOI: 10.1107/S1744309110022529

実験手法

X-RAY DIFFRACTION (1.6 Å)