3MP2

Crystal structure of transmissible gastroenteritis virus papain-like protease 1

3MP2 の概要

• エントリーDOI: 10.2210/pdb3mp2/pdb
• 分子名称: Non-structural protein 3, ZINC ION (3 entities in total)
• 機能のキーワード: papain-like protease, tgev, coronavirus, hydrolase
• 由来する生物種: Porcine transmissible gastroenteritis coronavirus (TGEV)
• 細胞内の位置: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6V2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23656.64

構造登録者

Wojdyla, J.A.,Manolaridis, I.,Tucker, P.A. (登録日: 2010-04-24, 公開日: 2010-09-08, 最終更新日: 2024-02-21)

• 主引用文献: Wojdyla, J.A.,Manolaridis, I.,van Kasteren, P.B.,Kikkert, M.,Snijder, E.J.,Gorbalenya, A.E.,Tucker, P.A.; Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates.; J.Virol., 84:10063-10073, 2010; PubMed: 20668092; DOI: 10.1128/JVI.00898-10

実験手法

X-RAY DIFFRACTION (2.5 Å)