3MOQ

Amyloid beta(18-41) peptide fusion with new antigen receptor variable domain from sharks

3MOQ の概要

• エントリーDOI: 10.2210/pdb3moq/pdb
• 分子名称: New antigen receptor variable domain,P3(40) peptide from Amyloid beta A4 protein,New antigen receptor variable domain (2 entities in total)
• 機能のキーワード: ab-ignar, ab-12y-2, receptor, amyloid, glycoprotein, membrane, protease inhibitor, serine protease inhibitor, transmembrane, amyloid beta fusion with ignar, chimera of immune system and amyloid peptide, immune system, neuropeptide
• 由来する生物種: Orectolobus maculatus (spotted wobbegong); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 53864.52

構造登録者

Streltsov, V.A. (登録日: 2010-04-23, 公開日: 2011-02-16, 最終更新日: 2023-11-01)

• 主引用文献: Streltsov, V.A.,Varghese, J.N.,Masters, C.L.,Nuttall, S.D.; Crystal Structure of the Amyloid-{beta} p3 Fragment Provides a Model for Oligomer Formation in Alzheimer's Disease; J.Neurosci., 31:1419-1426, 2011; PubMed: 21273426; DOI: 10.1523/JNEUROSCI.4259-10.2011

実験手法

X-RAY DIFFRACTION (2.054 Å)