3MJ4

Crystal structure of UDP-galactopyranose mutase in complex with phosphonate analog of UDP-galactopyranose

Summary for 3MJ4

• Entry DOI: 10.2210/pdb3mj4/pdb
• Descriptor: UDP-galactopyranose mutase, FLAVIN-ADENINE DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: udp-galactopyranose mutase, phosphonate analog, inhibitor, binding mode, isomerase
• Biological source: Deinococcus radiodurans
• Total number of polymer chains: 10
• Total formula weight: 472082.16

Authors

Karunan Partha, S.,Sadeghi-Khomami, A.,Slowski, K.,Kotake, T.,Thomas, N.R.,Jakeman, D.L.,Sanders, D.A.R. (deposition date: 2010-04-12, release date: 2010-10-20, Last modification date: 2023-09-06)

• Primary citation: Partha, S.K.,Sadeghi-Khomami, A.,Slowski, K.,Kotake, T.,Thomas, N.R.,Jakeman, D.L.,Sanders, D.A.; Chemoenzymatic Synthesis, Inhibition Studies, and X-ray Crystallographic Analysis of the Phosphono Analog of UDP-Galp as an Inhibitor and Mechanistic Probe for UDP-Galactopyranose Mutase.; J.Mol.Biol., 403:578-590, 2010; PubMed: 20850454; DOI: 10.1016/j.jmb.2010.08.053

Experimental method

X-RAY DIFFRACTION (2.65 Å)