3MJ4

Crystal structure of UDP-galactopyranose mutase in complex with phosphonate analog of UDP-galactopyranose

3MJ4 の概要

• エントリーDOI: 10.2210/pdb3mj4/pdb
• 分子名称: UDP-galactopyranose mutase, FLAVIN-ADENINE DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
• 機能のキーワード: udp-galactopyranose mutase, phosphonate analog, inhibitor, binding mode, isomerase
• 由来する生物種: Deinococcus radiodurans
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 472082.16

構造登録者

Karunan Partha, S.,Sadeghi-Khomami, A.,Slowski, K.,Kotake, T.,Thomas, N.R.,Jakeman, D.L.,Sanders, D.A.R. (登録日: 2010-04-12, 公開日: 2010-10-20, 最終更新日: 2023-09-06)

• 主引用文献: Partha, S.K.,Sadeghi-Khomami, A.,Slowski, K.,Kotake, T.,Thomas, N.R.,Jakeman, D.L.,Sanders, D.A.; Chemoenzymatic Synthesis, Inhibition Studies, and X-ray Crystallographic Analysis of the Phosphono Analog of UDP-Galp as an Inhibitor and Mechanistic Probe for UDP-Galactopyranose Mutase.; J.Mol.Biol., 403:578-590, 2010; PubMed: 20850454; DOI: 10.1016/j.jmb.2010.08.053

実験手法

X-RAY DIFFRACTION (2.65 Å)