3MCY
Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.
Summary for 3MCY
Entry DOI | 10.2210/pdb3mcy/pdb |
Descriptor | FimH, methyl 4'-(alpha-D-mannopyranosyloxy)biphenyl-3-carboxylate, GLYCEROL, ... (6 entities in total) |
Functional Keywords | lectin, mannoside, immunogobulin fold, carbohydrate binding protein |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 80090.97 |
Authors | Ford, B.A.,Hultgren, S.J. (deposition date: 2010-03-29, release date: 2010-06-16, Last modification date: 2023-09-06) |
Primary citation | Han, Z.,Pinkner, J.S.,Ford, B.,Obermann, R.,Nolan, W.,Wildman, S.A.,Hobbs, D.,Ellenberger, T.,Cusumano, C.K.,Hultgren, S.J.,Janetka, J.W. Structure-based drug design and optimization of mannoside bacterial FimH antagonists. J.Med.Chem., 53:4779-4792, 2010 Cited by PubMed: 20507142DOI: 10.1021/jm100438s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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