3MCY

Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.

3MCY の概要

• エントリーDOI: 10.2210/pdb3mcy/pdb
• 分子名称: FimH, methyl 4'-(alpha-D-mannopyranosyloxy)biphenyl-3-carboxylate, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: lectin, mannoside, immunogobulin fold, carbohydrate binding protein
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 80090.97

構造登録者

Ford, B.A.,Hultgren, S.J. (登録日: 2010-03-29, 公開日: 2010-06-16, 最終更新日: 2023-09-06)

• 主引用文献: Han, Z.,Pinkner, J.S.,Ford, B.,Obermann, R.,Nolan, W.,Wildman, S.A.,Hobbs, D.,Ellenberger, T.,Cusumano, C.K.,Hultgren, S.J.,Janetka, J.W.; Structure-based drug design and optimization of mannoside bacterial FimH antagonists.; J.Med.Chem., 53:4779-4792, 2010; PubMed: 20507142; DOI: 10.1021/jm100438s

実験手法

X-RAY DIFFRACTION (2.9 Å)