3MA6

Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1

Summary for 3MA6

• Entry DOI: 10.2210/pdb3ma6/pdb
• Descriptor: Calmodulin-domain protein kinase 1, 3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (3 entities in total)
• Functional Keywords: cdpk, parasitology, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, transferase, structural genomics, structural genomics consortium, sgc
• Biological source: Toxoplasma gondii
• Total number of polymer chains: 2
• Total formula weight: 69870.18

Authors

Wernimont, A.K.,Qiu, W.,Amani, M.,Artz, J.D.,Hassani, A.A.,Senisterra, G.,Vedadi, M.,Sibley, L.D.,Lourido, S.,Shokat, K.,Zhang, C.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Hui, R.,Lin, Y.H.,Structural Genomics Consortium (SGC) (deposition date: 2010-03-23, release date: 2010-07-21, Last modification date: 2017-11-08)

• Primary citation: Wernimont, A.K.,Qiu, W.,Amani, M.,Artz, J.D.,Hassani, A.A.,Senisterra, G.,Vedadi, M.,Sibley, L.D.,Lourido, S.,Shokat, K.,Zhang, C.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Hui, R.,Lin, Y.H.; Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1; To be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)