3M95

Crystal structure of autophagy-related protein Atg8 from the silkworm Bombyx mori

Summary for 3M95

• Entry DOI: 10.2210/pdb3m95/pdb
• Descriptor: Autophagy related protein Atg8 (2 entities in total)
• Functional Keywords: alpha slash beta, receptor, transport protein
• Biological source: Bombyx mori (Silk moth)
• Total number of polymer chains: 2
• Total formula weight: 29890.13

Authors

Teng, Y.-B.,Hu, C.,Zhang, X.,Jiang, Y.L.,Hu, H.-X.,Zhou, C.Z. (deposition date: 2010-03-20, release date: 2010-07-21, Last modification date: 2023-11-01)

Primary citation

Hu, C.,Zhang, X.,Teng, Y.-B.,Hu, H.-X.,Li, W.-F.
Structure of autophagy-related protein Atg8 from the silkworm Bombyx mori
Acta Crystallogr.,Sect.F, 66:787-790, 2010

PubMed Abstract: Autophagy-related protein Atg8 is ubiquitous in all eukaryotes. It is involved in the Atg8-PE ubiquitin-like conjugation system, which is essential for autophagosome formation. The structures of Atg8 from different species are very similar and share a ubiquitin-fold domain at the C-terminus. In the 2.40 A crystal structure of Atg8 from the silkworm Bombyx mori reported here, the ubiquitin fold at the C-terminus is preceded by two additional helices at the N-terminus.

PubMed: 20606273
DOI: 10.1107/S1744309110018464

Experimental method

X-RAY DIFFRACTION (2.4 Å)