3M3S

Crystal structure of SARS-COV main protease Asn214Ala mutant with authorize N-terminus

3M3S の概要

• エントリーDOI: 10.2210/pdb3m3s/pdb
• 関連するPDBエントリー: 2QC2 3M3T 3M3V
• 分子名称: 3C-like proteinase (2 entities in total)
• 機能のキーワード: sars coronavirus protease n214a mutation, hydrolase
• 由来する生物種: SARS coronavirus (SARS-CoV)
• 細胞内の位置: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6U8
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 67667.23

構造登録者

Shi, J.H.,Song, J.X. (登録日: 2010-03-10, 公開日: 2011-03-23, 最終更新日: 2023-11-01)

• 主引用文献: Shi, J.H.,Song, J.X.; Dynamical Inactivation of the Catalytic Machinery of the SARS-CoV 3C-Like Protease as Triggered by the N214A Mutation on the Extra Domain; To be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)