3M3F
PEPA bound to the ligand binding domain of GluA3 (flop form)
Summary for 3M3F
| Entry DOI | 10.2210/pdb3m3f/pdb |
| Related | 3M3K 3M3L |
| Descriptor | Glutamate receptor 3, GLUTAMIC ACID, 2-[2,6-difluoro-4-({2-[(phenylsulfonyl)amino]ethyl}sulfanyl)phenoxy]acetamide, ... (5 entities in total) |
| Functional Keywords | glutamate receptor, glua3, glur3, ampa receptor, neurotransmitter receptor, s1s2, transport protein |
| Biological source | Rattus norvegicus (brown rat,rat,rats) More |
| Cellular location | Cell membrane ; Multi-pass membrane protein : P19492 |
| Total number of polymer chains | 1 |
| Total formula weight | 29650.78 |
| Authors | Ahmed, A.H.,Ptak, C.P.,Oswald, R.E. (deposition date: 2010-03-09, release date: 2010-03-23, Last modification date: 2023-09-06) |
| Primary citation | Ahmed, A.H.,Ptak, C.P.,Oswald, R.E. Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA. Biochemistry, 49:2843-2850, 2010 Cited by PubMed: 20199107DOI: 10.1021/bi1000678 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report
