3M01

The Crystal Structure of 5-epi-aristolochene synthase complexed with (2-trans,6-trans)-2-fluorofarnesyl diphosphate

3M01 の概要

• エントリーDOI: 10.2210/pdb3m01/pdb
• 関連するPDBエントリー: 3M00 3M02
• 分子名称: Aristolochene synthase, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: plant terpenoid cyclase, 5-epi-aristolochene synthase, lyase, metal-binding domain, (2-trans, 6-trans)-2-fluorofarnesyl diphosphate, magnesium, metal-binding
• 由来する生物種: Nicotiana tabacum (American tobacco,tobacco)
• 細胞内の位置: Cytoplasm: Q40577
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 63793.02

構造登録者

Noel, J.P.,Dellas, N.,Faraldos, J.A.,Zhao, M.,Hess Jr., B.A.,Smentek, L.,Coates, R.M.,O'Maille, P.E. (登録日: 2010-03-02, 公開日: 2010-07-07, 最終更新日: 2023-09-06)

• 主引用文献: Noel, J.P.,Dellas, N.,Faraldos, J.A.,Zhao, M.,Hess, B.A.,Smentek, L.,Coates, R.M.,O'Maille, P.E.; Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.; Acs Chem.Biol., 5:377-392, 2010; PubMed: 20175559; DOI: 10.1021/cb900295g

実験手法

X-RAY DIFFRACTION (2.6 Å)