3LZJ

RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine

Summary for 3LZJ

• Entry DOI: 10.2210/pdb3lzj/pdb
• Related: 1IG9 1IH7 3LZI
• Descriptor: DNA polymerase, DNA (5'-D(P*TP*CP*AP*(8OG)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... (6 entities in total)
• Functional Keywords: dna polymerase, replication fidelity, 7, 8-dihydro-8-oxoguanine, polymerase-dna-dntp ternary complex, transferase-dna complex, transferase/dna
• Biological source: Enterobacteria phage RB69 (Bacteriophage RB69)
• Total number of polymer chains: 3
• Total formula weight: 114715.69

Authors

Wang, M.,Beckman, J.,Blaha, G.,Wang, J.,Konigsberg, W.H. (deposition date: 2010-03-01, release date: 2010-05-19, Last modification date: 2024-02-21)

• Primary citation: Beckman, J.,Wang, M.,Blaha, G.,Wang, J.,Konigsberg, W.H.; Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .; Biochemistry, 49:4116-4125, 2010; PubMed: 20411947; DOI: 10.1021/bi100102s

Experimental method

X-RAY DIFFRACTION (2.05 Å)