3LXJ

Crystal Structure of the Bromodomain of Human AAA domain containing 2B (ATAD2B)

Summary for 3LXJ

• Entry DOI: 10.2210/pdb3lxj/pdb
• Descriptor: ATPase family AAA domain-containing protein 2B, ISOPROPYL ALCOHOL (3 entities in total)
• Functional Keywords: atpase family, aaa domain containing 2b, atad2b, bromodomain, structural genomics consortium, sgc, atp-binding, nucleotide-binding, phosphoprotein, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q9ULI0
• Total number of polymer chains: 4
• Total formula weight: 63636.85

Authors

Filippakopoulos, P.,Keates, T.,Picaud, S.,Fedorov, O.,Krojer, T.,Vollmar, M.,Muniz, J.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-02-25, release date: 2010-03-09, Last modification date: 2023-09-06)

• Primary citation: Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.; Histone recognition and large-scale structural analysis of the human bromodomain family.; Cell(Cambridge,Mass.), 149:214-231, 2012; PubMed: 22464331; DOI: 10.1016/j.cell.2012.02.013

Experimental method

X-RAY DIFFRACTION (2.33 Å)