3LWP

Structure of H/ACA RNP bound to a substrate RNA containing 5BrdU

3LWP の概要

• エントリーDOI: 10.2210/pdb3lwp/pdb
• 関連するPDBエントリー: 3LWO 3LWQ 3LWR 3LWV
• 分子名称: Pseudouridine synthase Cbf5, Ribosome biogenesis protein Nop10, 50S ribosomal protein L7Ae, ... (7 entities in total)
• 機能のキーワード: h/aca pseudouridine synthase, isomerase, trna processing, ribonucleoprotein, ribosome biogenesis, rrna processing, ribosomal protein, rna-binding, isomerase-rna binding protein-rna complex, isomerase/rna binding protein/rna
• 由来する生物種: Pyrococcus furiosus; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 82288.32

構造登録者

Zhou, J.,Liang, B.,Lv, C.,Yang, W.,Li, H. (登録日: 2010-02-24, 公開日: 2010-07-14, 最終更新日: 2011-07-13)

• 主引用文献: Zhou, J.,Lv, C.,Liang, B.,Chen, M.,Yang, W.,Li, H.; Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.; J.Mol.Biol., 401:690-695, 2010; PubMed: 20615421; DOI: 10.1016/j.jmb.2010.06.061

実験手法

X-RAY DIFFRACTION (2.5 Å)