3LQS
Complex Structure of D-Amino Acid Aminotransferase and 4-amino-4,5-dihydro-thiophenecarboxylic acid (ADTA)
Summary for 3LQS
Entry DOI | 10.2210/pdb3lqs/pdb |
Related | 3DAA |
Descriptor | D-alanine aminotransferase, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, ACETIC ACID, ... (4 entities in total) |
Functional Keywords | plp aminotransferase, mechanism-based inhibitor, stereo-specificity, r-adta, aminotransferase, pyridoxal phosphate, transferase |
Biological source | Bacillus sp. |
Total number of polymer chains | 2 |
Total formula weight | 64929.88 |
Authors | Lepore, B.W.,Liu, D.,Peng, Y.,Fu, M.,Yasuda, C.,Manning, J.M.,Silverman, R.B.,Ringe, D. (deposition date: 2010-02-10, release date: 2010-03-16, Last modification date: 2024-02-21) |
Primary citation | Lepore, B.W.,Liu, D.,Peng, Y.,Fu, M.,Yasuda, C.,Manning, J.M.,Silverman, R.B.,Ringe, D. Chiral discrimination among aminotransferases: inactivation by 4-amino-4,5-dihydrothiophenecarboxylic acid. Biochemistry, 49:3138-3147, 2010 Cited by PubMed: 20192272DOI: 10.1021/bi902052x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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