3LOG

Crystal structure of MbtI from Mycobacterium tuberculosis

3LOG の概要

• エントリーDOI: 10.2210/pdb3log/pdb
• 分子名称: Isochorismate synthase/isochorismate-pyruvate lyase mbtI, SUCCINIC ACID, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: chorismate, salicylate, anthranilate, isochorismate, isochorismate synthase, isochorismate lyase, ion transport, isomerase, lyase, metal-binding, multifunctional enzyme, transport
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 196442.86

構造登録者

Bulloch, E.M.M.,Lott, J.S.,Baker, E.N.,Johnston, J.M. (登録日: 2010-02-03, 公開日: 2011-02-09, 最終更新日: 2023-11-01)

• 主引用文献: Manos-Turvey, A.,Bulloch, E.M.,Rutledge, P.J.,Baker, E.N.,Lott, J.S.,Payne, R.J.; Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI).; Chemmedchem, 5:1067-1079, 2010; PubMed: 20512795; DOI: 10.1002/cmdc.201000137

実験手法

X-RAY DIFFRACTION (1.73 Å)