3LN5

Crystal structure of HLA-B*4104 in complex with a 11mer self-peptide derived from S-methyl-5-thioadenosine phosphorylase

3LN5 の概要

• エントリーDOI: 10.2210/pdb3ln5/pdb
• 関連するPDBエントリー: 3LN4
• 分子名称: HLA class I histocompatibility antigen, B-41 alpha chain, Beta-2-microglobulin, 11-mer peptide from S-methyl-5'-thioadenosine phosphorylase, ... (4 entities in total)
• 機能のキーワード: immunoglobulin domain, immune response, major histocompatibility complex class i, mhc-i peptide complex, peptide-binding motifs, disulfide bond, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P30479; Secreted: P61769; Cytoplasm: Q13126
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44775.50

構造登録者

Theodossis, A.,Gras, S.,Rossjohn, J. (登録日: 2010-02-02, 公開日: 2010-10-20, 最終更新日: 2023-11-01)

• 主引用文献: Bade-Doding, C.,Theodossis, A.,Gras, S.,Kjer-Nielsen, L.,Eiz-Vesper, B.,Seltsam, A.,Huyton, T.,Rossjohn, J.,McCluskey, J.,Blasczyk, R.; The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family; Haematologica, 96:110-118, 2011; PubMed: 20934997; DOI: 10.3324/haematol.2010.030924

実験手法

X-RAY DIFFRACTION (1.9 Å)