3LLP

1.8 Angstrom human fascin 1 crystal structure

Summary for 3LLP

Entry DOI	10.2210/pdb3llp/pdb
Descriptor	Fascin, GLYCEROL, POTASSIUM ION, ... (7 entities in total)
Functional Keywords	beta-trefoil, actin bundling protein, cancer, metastasis, cell migration, acetylation, actin-binding, cytoplasm, phosphoprotein, protein binding
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton: Q16658
Total number of polymer chains	2
Total formula weight	110828.25
Authors	Chen, L.,Yang, S.,Jakoncic, J.,Zhang, J.J.,Huang, X.-Y. (deposition date: 2010-01-29, release date: 2010-04-07, Last modification date: 2024-02-21)
Primary citation	Chen, L.,Yang, S.,Jakoncic, J.,Zhang, J.J.,Huang, X.Y. Migrastatin analogues target fascin to block tumour metastasis. Nature, 464:1062-1066, 2010 Cited by PubMed: 20393565 DOI: 10.1038/nature08978 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation