3LL8
Crystal Structure of Calcineurin in Complex with AKAP79 Peptide
Summary for 3LL8
Entry DOI | 10.2210/pdb3ll8/pdb |
Descriptor | AKAP79 peptide, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, ... (8 entities in total) |
Functional Keywords | protein-peptide docking, protein targeting, calcineurin, akap79, beta-augmentation, calmodulin-binding, membrane, hydrolase, iron, metal-binding, nucleus, phosphoprotein, protein phosphatase, lipoprotein, myristate, hydrolase-calcium binding protein complex, hydrolase/calcium binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane ; Lipid-anchor : P24588 Cell membrane : Q08209 Cytoplasm, cytosol : P63098 |
Total number of polymer chains | 5 |
Total formula weight | 119733.84 |
Authors | Li, H.,Hogan, P.G. (deposition date: 2010-01-28, release date: 2011-01-12, Last modification date: 2024-02-21) |
Primary citation | Li, H.,Pink, M.D.,Murphy, J.G.,Stein, A.,Dell'acqua, M.L.,Hogan, P.G. Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling. Nat.Struct.Mol.Biol., 19:337-345, 2012 Cited by PubMed: 22343722DOI: 10.1038/nsmb.2238 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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