3LL8

Crystal Structure of Calcineurin in Complex with AKAP79 Peptide

Summary for 3LL8

Entry DOI	10.2210/pdb3ll8/pdb
Descriptor	AKAP79 peptide, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, ... (8 entities in total)
Functional Keywords	protein-peptide docking, protein targeting, calcineurin, akap79, beta-augmentation, calmodulin-binding, membrane, hydrolase, iron, metal-binding, nucleus, phosphoprotein, protein phosphatase, lipoprotein, myristate, hydrolase-calcium binding protein complex, hydrolase/calcium binding protein
Biological source	Homo sapiens (human) More
Cellular location	Membrane ; Lipid-anchor : P24588 Cell membrane : Q08209 Cytoplasm, cytosol : P63098
Total number of polymer chains	5
Total formula weight	119733.84
Authors	Li, H.,Hogan, P.G. (deposition date: 2010-01-28, release date: 2011-01-12, Last modification date: 2024-02-21)
Primary citation	Li, H.,Pink, M.D.,Murphy, J.G.,Stein, A.,Dell'acqua, M.L.,Hogan, P.G. Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling. Nat.Struct.Mol.Biol., 19:337-345, 2012 Cited by PubMed: 22343722 DOI: 10.1038/nsmb.2238 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation