3LL8

Crystal Structure of Calcineurin in Complex with AKAP79 Peptide

3LL8 の概要

分子名称AKAP79 peptide, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, ... (8 entities in total)
機能のキーワードprotein-peptide docking, protein targeting, calcineurin, akap79, beta-augmentation, calmodulin-binding, membrane, hydrolase, iron, metal-binding, nucleus, phosphoprotein, protein phosphatase, lipoprotein, myristate, hydrolase-calcium binding protein complex, hydrolase/calcium binding protein
由来する生物種Homo sapiens (human)
細胞内の位置Membrane ; Lipid-anchor  P24588
Cell membrane  Q08209
Cytoplasm, cytosol  P63098
ポリマー鎖数5
分子量合計119733.84
構造登録者
Li, H.,Hogan, P.G. (登録日: 2010-01-28, 公開日: 2011-01-12, 最終更新日: 2017-11-01)
主引用文献
Li, H.,Pink, M.D.,Murphy, J.G.,Stein, A.,Dell'acqua, M.L.,Hogan, P.G.
Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling.
Nat.Struct.Mol.Biol., 19:337-345, 2012
PubMed: 22343722 (主引用文献が同じPDBエントリー)
DOI: 10.1038/nsmb.2238
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22970.2%4.7%5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード