3LL8

Crystal Structure of Calcineurin in Complex with AKAP79 Peptide

3LL8 の概要

• エントリーDOI: 10.2210/pdb3ll8/pdb
• 分子名称: AKAP79 peptide, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, ... (8 entities in total)
• 機能のキーワード: protein-peptide docking, protein targeting, calcineurin, akap79, beta-augmentation, calmodulin-binding, membrane, hydrolase, iron, metal-binding, nucleus, phosphoprotein, protein phosphatase, lipoprotein, myristate, hydrolase-calcium binding protein complex, hydrolase/calcium binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane ; Lipid-anchor : P24588; Cell membrane : Q08209; Cytoplasm, cytosol : P63098
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 119733.84

構造登録者

Li, H.,Hogan, P.G. (登録日: 2010-01-28, 公開日: 2011-01-12, 最終更新日: 2024-02-21)

• 主引用文献: Li, H.,Pink, M.D.,Murphy, J.G.,Stein, A.,Dell'acqua, M.L.,Hogan, P.G.; Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling.; Nat.Struct.Mol.Biol., 19:337-345, 2012; PubMed: 22343722; DOI: 10.1038/nsmb.2238

実験手法

X-RAY DIFFRACTION (2 Å)