3LKN

Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1918 strain

3LKN の概要

• エントリーDOI: 10.2210/pdb3lkn/pdb
• 関連するPDBエントリー: 3LKO 3LKP 3LKQ 3LKR 3LKS
• 分子名称: HLA class I histocompatibility antigen, B-35 alpha chain, Beta-2-microglobulin, NP418 epitope from 1918 influenza strain, ... (4 entities in total)
• 機能のキーワード: hla b*3501, np418 epitope, influenza, swine-flu, t cell immunity, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, amyloid, amyloidosis, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P30685; Secreted: P61769
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44897.91

構造登録者

Gras, S.,Kedzierski, L.,Valkenburg, S.A.,Liu, Y.C.,Denholm, J.,Richards, M.,Rimmelzwaan, G.F.,Doherty, P.C.,Turner, S.J.,Rossjohn, J.,Kedzierska, K. (登録日: 2010-01-27, 公開日: 2010-07-07, 最終更新日: 2023-09-06)

• 主引用文献: Gras, S.,Kedzierski, L.,Valkenburg, S.A.,Laurie, K.,Liu, Y.C.,Denholm, J.T.,Richards, M.J.,Rimmelzwaan, G.F.,Kelso, A.,Doherty, P.C.,Turner, S.J.,Rossjohn, J.,Kedzierska, K.; Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.; Proc.Natl.Acad.Sci.USA, 107:12599-12604, 2010; PubMed: 20616031; DOI: 10.1073/pnas.1007270107

実験手法

X-RAY DIFFRACTION (2 Å)