3LIR
Human MMP12 in complex with non-zinc chelating inhibitor
Summary for 3LIR
Entry DOI | 10.2210/pdb3lir/pdb |
Related | 3LIK 3LIL 3LJG |
Related PRD ID | PRD_000800 |
Descriptor | Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | mmp12 elastase non-chelating inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 18416.25 |
Authors | Stura, E.A.,Dive, V.,Devel, L.,Czarny, B.,Vera, L.,Beau, F. (deposition date: 2010-01-25, release date: 2010-09-01, Last modification date: 2023-09-06) |
Primary citation | Devel, L.,Garcia, S.,Czarny, B.,Beau, F.,LaJeunesse, E.,Vera, L.,Georgiadis, D.,Stura, E.,Dive, V. Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation. J.Biol.Chem., 285:35900-35909, 2010 Cited by PubMed: 20817735DOI: 10.1074/jbc.M110.139634 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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