3LH4

Crystal Structure of Sialostatin L2

3LH4 の概要

• エントリーDOI: 10.2210/pdb3lh4/pdb
• 分子名称: Secreted cystatin, SULFATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: beta sheet, cystatin, protease inhibitor, thiol protease inhibitor, hydrolase inhibitor
• 由来する生物種: Ixodes scapularis (blacklegged tick, shoulder tick)
• 細胞内の位置: Secreted : B7PKZ1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12963.23

構造登録者

Andersen, J.F.,Kotsyfakis, M.,Salat, J.,Horka, H. (登録日: 2010-01-21, 公開日: 2010-09-29, 最終更新日: 2017-11-01)

• 主引用文献: Kotsyfakis, M.,Horka, H.,Salat, J.,Andersen, J.F.; The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model.; Mol.Microbiol., 77:456-470, 2010; PubMed: 20545851; DOI: 10.1111/j.1365-2958.2010.07220.x

実験手法

X-RAY DIFFRACTION (1.8 Å)