3LCC

Structure of a SAM-dependent halide methyltransferase from Arabidopsis thaliana

3LCC の概要

• エントリーDOI: 10.2210/pdb3lcc/pdb
• 分子名称: Putative methyl chloride transferase, S-ADENOSYL-L-HOMOCYSTEINE, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: halide methyltransferase, transferase
• 由来する生物種: Arabidopsis thaliana (thale cress)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26805.64

構造登録者

Schmidberger, J.W.,O'Hagan, D.,Naismith, J.H. (登録日: 2010-01-10, 公開日: 2010-05-19, 最終更新日: 2023-11-01)

主引用文献

Schmidberger, J.W.,James, A.B.,Edwards, R.,Naismith, J.H.,O'Hagan, D.
Halomethane Biosynthesis: Structure of a SAM-Dependent Halide Methyltransferase from Arabidopsis thaliana
Angew.Chem.Int.Ed.Engl., 49:3646-3648, 2010

PubMed Abstract: A product structure of the halomethane producing enzyme in plants () is reported and a model for presentation of chloride/bromide ion to the methyl group of S-adenosyl-L-methionine (SAM) is presented to rationalise nucleophilic halide attack for halomethane production, gaseous natural products that are produced globally.

PubMed: 20376845
DOI: 10.1002/anie.201000119

実験手法

X-RAY DIFFRACTION (1.8 Å)