3L9Q
Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain
Summary for 3L9Q
| Entry DOI | 10.2210/pdb3l9q/pdb |
| Descriptor | DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | pol alpha, primase, dna replication, polymerase, iron-sulfur cluster, dna-binding, dna-directed rna polymerase, iron, iron-sulfur, metal-binding, nucleotidyltransferase, phosphoprotein, primosome, transcription, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 46219.16 |
| Authors | Vaithiyalingam, S.,Eichman, B.F.,Chazin, W.J. (deposition date: 2010-01-05, release date: 2010-07-14, Last modification date: 2011-11-16) |
| Primary citation | Vaithiyalingam, S.,Warren, E.M.,Eichman, B.F.,Chazin, W.J. Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Proc.Natl.Acad.Sci.USA, 107:13684-13689, 2010 Cited by PubMed: 20643958DOI: 10.1073/pnas.1002009107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.698 Å) |
Structure validation
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