3L3U

Crystal structure of the HIV-1 integrase core domain to 1.4A

Summary for 3L3U

Entry DOI	10.2210/pdb3l3u/pdb
Related	1bl3 1ex4 3L3V
Descriptor	POL polyprotein, SULFATE ION (3 entities in total)
Functional Keywords	dna integration, aids, integrase, endonuclease, polynucleotidyl transferase, dna binding, viral protein
Biological source	Human immunodeficiency virus 1
Total number of polymer chains	2
Total formula weight	35892.54
Authors	Wielens, J.,Chalmers, D.K.,Scanlon, M.J.,Parker, M.W. (deposition date: 2009-12-17, release date: 2010-03-31, Last modification date: 2023-11-01)
Primary citation	Wielens, J.,Headey, S.J.,Jeevarajah, D.,Rhodes, D.I.,Deadman, J.,Chalmers, D.K.,Scanlon, M.J.,Parker, M.W. Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site. Febs Lett., 584:1455-1462, 2010 Cited by PubMed: 20227411 DOI: 10.1016/j.febslet.2010.03.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation