3L0H

Crystal Structure Analysis of W21A mutant of human GSTA1-1 in complex with S-hexylglutathione

Summary for 3L0H

• Entry DOI: 10.2210/pdb3l0h/pdb
• Related: 3KTL
• Descriptor: Glutathione S-transferase A1, S-HEXYLGLUTATHIONE (3 entities in total)
• Functional Keywords: thioredoxin, s-hexylglutathione, glutathione s-transferase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P08263
• Total number of polymer chains: 2
• Total formula weight: 51894.96

Authors

Fanucchi, S.,Achilonu, I.A.,Adamson, R.J.,Fernandes, M.A.,Burke, J.P.,Dirr, H.W. (deposition date: 2009-12-10, release date: 2010-01-12, Last modification date: 2024-02-21)

• Primary citation: Balchin, D.,Fanucchi, S.,Achilonu, I.,Adamson, R.J.,Burke, J.,Fernandes, M.,Gildenhuys, S.,Dirr, H.W.; Stability of the domain interface contributes towards the catalytic function at the H-site of class alpha glutathione transferase A1-1.; Biochim.Biophys.Acta, 1804:2228-2233, 2010; PubMed: 20833278; DOI: 10.1016/j.bbapap.2010.09.003

Experimental method

X-RAY DIFFRACTION (2.13 Å)