3KWY

Crystal structure of RXRalpha ligand binding domain in complex with triphenyltin and a coactivator fragment

3KWY の概要

• エントリーDOI: 10.2210/pdb3kwy/pdb
• 分子名称: Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2 peptide, triphenylstannanyl, ... (5 entities in total)
• 機能のキーワード: nuclear receptor transcription organotin, dna-binding, host-virus interaction, isopeptide bond, metal-binding, nucleus, receptor, transcription, transcription regulation, zinc-finger, activator, phosphoprotein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P19793 Q15596
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29258.45

構造登録者

le Maire, A.,Bourguet, W. (登録日: 2009-12-02, 公開日: 2010-01-19, 最終更新日: 2023-09-06)

• 主引用文献: le Maire, A.,Bourguet, W.,Balaguer, P.; A structural view of nuclear hormone receptor: endocrine disruptor interactions.; Cell.Mol.Life Sci., 67:1219-1237, 2010; PubMed: 20063036; DOI: 10.1007/s00018-009-0249-2

実験手法

X-RAY DIFFRACTION (2.3 Å)