3KSY
Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS)
Summary for 3KSY
Entry DOI | 10.2210/pdb3ksy/pdb |
Descriptor | Son of sevenless homolog 1 (1 entity in total) |
Functional Keywords | ras, sos, ras activator, son of sevenless, disease mutation, guanine-nucleotide releasing factor, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 121967.73 |
Authors | Gureasko, J.,Kuchment, O.,Kuriyan, J. (deposition date: 2009-11-24, release date: 2010-02-16, Last modification date: 2024-02-21) |
Primary citation | Gureasko, J.,Kuchment, O.,Makino, D.L.,Sondermann, H.,Bar-Sagi, D.,Kuriyan, J. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless. Proc.Natl.Acad.Sci.USA, 107:3430-3435, 2010 Cited by PubMed: 20133692DOI: 10.1073/pnas.0913915107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.178 Å) |
Structure validation
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