3KMS

G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure

Summary for 3KMS

• Entry DOI: 10.2210/pdb3kms/pdb
• Related: 1U09 1WNE 2D7S 2E9T 2E9Z 2F8E 3KLV 3KMQ 3KNA 3KOA
• Descriptor: 3D polymerase, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*C)-3'), ... (5 entities in total)
• Functional Keywords: 3d, polymerase, ribavirin, foot-and mouth disease virus, rna dependent rna polymerase, transferase-rna complex, transferase/rna
• Biological source: Foot-and-mouth disease virus - type C
• Cellular location: Picornain 3C: Host cytoplasm (By similarity): Q9QCE3
• Total number of polymer chains: 3
• Total formula weight: 57338.41

Authors

Ferrer-Orta, C.,Verdaguer, N.,Perez-Luque, R. (deposition date: 2009-11-11, release date: 2010-07-07, Last modification date: 2024-03-20)

• Primary citation: Ferrer-Orta, C.,Sierra, M.,Agudo, R.,de la Higuera, I.,Arias, A.,Perez-Luque, R.,Escarmis, C.,Domingo, E.,Verdaguer, N.; Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin; J.Virol., 84:6188-6199, 2010; PubMed: 20392853; DOI: 10.1128/JVI.02420-09

Experimental method

X-RAY DIFFRACTION (2.2 Å)