3KK5
Crystal structure of PBCV-1 VP54 fitted into a cryo-EM reconstruction of the virophage Sputnik
Summary for 3KK5
| Entry DOI | 10.2210/pdb3kk5/pdb |
| Related | 1M3Y |
| EMDB information | 1662 |
| Descriptor | Major capsid protein (1 entity in total) |
| Functional Keywords | double jellyroll, capsid protein, late protein, virion, icosahedral virus, virus |
| Biological source | Acanthamoeba polyphaga (amoebae) |
| Total number of polymer chains | 13 |
| Total formula weight | 626595.13 |
| Authors | Sun, S.,Rossmann, M.G. (deposition date: 2009-11-04, release date: 2009-11-17, Last modification date: 2024-02-21) |
| Primary citation | Sun, S.,La Scola, B.,Bowman, V.D.,Ryan, C.M.,Whitelegge, J.P.,Raoult, D.,Rossmann, M.G. Structural studies of the sputnik virophage. J.Virol., 84:894-897, 2010 Cited by PubMed Abstract: The virophage Sputnik is a satellite virus of the giant mimivirus and is the only satellite virus reported to date whose propagation adversely affects its host virus' production. Genome sequence analysis showed that Sputnik has genes related to viruses infecting all three domains of life. Here, we report structural studies of Sputnik, which show that it is about 740 A in diameter, has a T=27 icosahedral capsid, and has a lipid membrane inside the protein shell. Structural analyses suggest that the major capsid protein of Sputnik is likely to have a double jelly-roll fold, although sequence alignments do not show any detectable similarity with other viral double jelly-roll capsid proteins. Hence, the origin of Sputnik's capsid might have been derived from other viruses prior to its association with mimivirus. PubMed: 19889775DOI: 10.1128/JVI.01957-09 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (10.6 Å) |
Structure validation
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